Our research interests are in the interdisciplinary areas of materials, analytical, electrochemistry, catalysis, and emerging nanotechnology fields. The overall direction is the design, fabrication, characterization, and application of novel nanostructured materials and strategies for addressing challenging issues in chemical/biological sensors, catalysis, biomedical devices, and energy and environment. Our current research explores both fundamental and applied aspects in this general direction. The most recent projects explore molecularly-engineered nanomaterials with novel sensing, catalytic, optical, magnetic, and electronic functions, and probe the mechanistic details of chemistry and biochemistry at surfaces and interfaces.
One example of our approaches involves exploration of core-shell nanoparticles as building blocks towards functional nanostructures. The manipulation of size, shape, surface and interparticle spatial properties leads to novel chemical/biological functions, e.g., catalysts, sensors, and bio-probes for specific binding events of proteins, DNAs, and amino acids. The fundamental understanding of the interfacial phenomena and nanoscale chemistry at the molecular level has not only led us to the development of a number of important technologies in design and fabrication of nanoparticles and nanomaterials, but also the exploration of their industrial applications in microsensor technology, fuel cell technology and biomedical probes.
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- I-I. S. Lim, U. Chandrachud, L. Wang, S. Gal, C.J. Zhong, "Assembly-Disassembly of DNAs and Gold Nanoparticles: A Strategy of Intervention Based on Oligonucleotides and Restriction Enzymes", Anal. Chem., 2008, 80, 6038-6044.
- J. Luo, L.Y. Wang, D. Mott, P.N. Njoki, Y. Lin, T. He, Z. Xu, B. Wanjala, S. I-Im Lim, C.J. Zhong, "Core@Shell Nanoparticles as Electrocatalysts for Fuel Cell Reactions", Adv. Mater., 2008, 20, 4342–4347.
- I-I. S. Lim, D. Mott, W. Ip, P. N. Njoki, Y. Pan, S. Zhou, C. J. Zhong, "Interparticle Interactions in Glutathione Mediated Assembly of Gold Nanoparticles", Lamgmuir, 2008, 24, 8857-8863.
- H. Y. Park, M. J. Schadt, L. Wang, I-Im S. Lim, P. N. Njoki, S. H. Kim, M.-Y. Jang, J. Luo, C. J. Zhong, "Fabrication of Magnetic Core@Shell Fe-Oxide@Au Nanoparticles for Interfacial Bio-activity and Bio-separation", Langmuir, 2007, 23, 9050-9056.
- P. N. Njoki, S. I-Im Lim, D. Mott, H.-Y. Park, B. Khan, S. Mishra, R. Sujakumar, J. Luo, C. J. Zhong, "Size Correlation of Optical and Spectroscopic Properties for Gold Nanoparticles", J. Phys. Chem., C, 2007, 111, 14664-14669.
- S. Lim, C. Vaiana, Z. Zhang, Y. Zhang, D. L. An, C. J. Zhong, "X-Shaped Rigid Arylethynes to Mediate the Assembly of Nanoparticles", J. Am. Chem. Soc., 2007, 129, 5368-5369.
- D. Mott, J. Luo, P. Njoki, Y. Lin, L. Wang, C. J. Zhong, "Synergistic Activity of Gold-Platinum Alloy Nanoparticle Catalysts", Catalysis Today, 2007, 122, 378-385.
- L. Wang, X. Shi, N. N. Kariuki, M. Schadt, G. R. Wang, Q. Rendeng, J. Choi, J. Luo, S. Lu, C. J. Zhong, "Array of Molecularly-Mediated Thin Film Assemblies of Nanoparticles: Correlation of Vapor Sensing with Interparticle Spatial Properties", J. Am. Chem. Soc., 2007, 129, 2161-2170.
- I-I. S. Lim, W. Ip, E. Crew, P. Njoki, D. Mott, Y. Pan, S. Zhou, C.J. Zhong, "Homocysteine-Mediated Reactivity and Assembly of Gold Nanoparticles", Langmuir, 2007, 23, 826-833.
- M. J. Schadt, W. Cheung, J. Luo, C. J. Zhong, "Molecularly-Tuned Size Selectivity in Thermal Processing of Gold Nanoparticles", Chem. Mater., 2006, 18, 5147-5148.
- P. N. Njoki, A. Jacob, B. Khan, J. Luo, C. J. Zhong, "Formation of Gold Nanoparticles Catalyzed by Platinum Nanoparticles: Assessment of the Catalytic Mechanism", J. Phys. Chem., B. 2006, 110, 22503-22509.
- T. He, E. Kreidler, L. Xiong, J. Luo, C.J. Zhong, "Alloy Electrocatalysts: Combinatorial Discovery and Nanosynthesis", J. Electrochem. Soc., 2006, 153, A1637-1643.
- I. S. Lim, F. Goroleski, D. Mott, N. Kariuki, W. Ip, J. Luo, C. J. Zhong, "Adsorption of Cyanine Dyes on Gold Nanoparticles and Formation of J-Aggregates in the Nanoparticle Assembly", J. Phys. Chem., B. 2006, 110, 6673-6682.
- J. Luo, L. Wang, D. Mott, P. Njoki, N. Kariuki, C. J. Zhong, T. He, "Ternary Alloy Nanoparticles with Controllable Sizes and Composition and Electrocatalytic Activity", J. Mater. Chem., 2006, 16, 1665-1673.
- J. Luo, P. Njoki, Y. Lin, L. Wang, D. Mott, C. J. Zhong, "Activity-Composition Correlation of AuPt Alloy Nanoparticle Catalysts in Electrocatalytic Reduction of Oxygen", Electrochem. Comm., 2006, 8, 581-587.
- J. Luo, N. Kariuki, L. Han, L. Wang, C. J. Zhong, T. He, "Preparation and Characterization of Carbon-supported PtVFe Electrocatalysts", Electrochim. Acta, 2006, 51, 4821-4827.
- J. Luo, P. Njoki, Y. Lin, D. Mott, L. Wang, C. J. Zhong, "Characterization of Carbon-Supported AuPt Nanoparticles for Electrocatalytic Methanol Oxidation Reaction", Langmuir, 2006, 22, 2892-2898.
- N.N. Kariuki, J. Luo, A. Hassan, I. S. Lim, L. Wang, C. J. Zhong, "Assembly of Bimetallic Gold-Silver Nanoparticles via Selective Interparticle Dicarboxylate-Silver Linkages", Chem. Mater., 2006, 18, 123-132.
- L. Wang, J. Luo, Q. Fan, M. Suzuki, I. S. Suzuki, M.H. Engelhard, Y. Lin, N. Kim, Jian Q. Wang,C. J. Zhong, "Monodispersed Iron Oxide-Gold Core-Shell Nanoparticles", J. Phys. Chem., B. 2005, 109, 21593-21601.
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